Hyaluronic Acid:
Hyaluronic acid (HA), also known as hyaluronic acid, is a naturally occurring component of the human body and is a transparent gel-like substance. It has a strong moisturizing ability and can absorb a large amount of water, keeping the skin moisturized and elastic.
Overview of Hyaluronic Acid Dermal Fillers:
Hyaluronic acid dermal fillers are an injectable product widely used in the field of medical beauty. Its main ingredient, hyaluronic acid (HA), is a glycosaminoglycan naturally present in human skin, joints and connective tissue. As the most popular non-permanent soft tissue filling material, hyaluronic acid fillers are implanted into the dermis or subcutaneous tissue through injection, which can instantly improve facial wrinkles, increase tissue volume, reshape facial contours, and stimulate collagen production to achieve a rejuvenating effect.
Basic properties of hyaluronic acid:
1. Excellent water retention capacity: Each gram of hyaluronic acid can bind 1,000 times its weight in water, making it one of the best moisturizing substances found in nature.
2. Viscoelasticity: Hyaluronic acid solution has both viscosity and elasticity, which can provide structural support and shock absorption for tissues.
3. Biocompatibility: As a natural component of the human body, hyaluronic acid rarely causes immune reactions or allergies.
4. Degradability: It can be naturally metabolized by hyaluronidase in the body and will not remain in the body permanently.
The three dimensions of molecular weight:
- Voluma filler: The largest molecular weight (>2×10⁶Da), high cross-linking, viscous texture, and strong support. Suitable for injection in the upper layer of the periosteum to achieve contour changes such as nose bridge heightening and chin shaping, and the effect lasts for 12-24 months.
- DERM filler: Medium molecular weight, moderate flexibility. Mainly injected into the deep dermis to the subcutaneous layer, improve nasolabial folds, apple muscle depressions and moderate wrinkles, and the effect lasts for 9-12 months.
- Fine filler (non-cross-linked or low cross-linked): small molecular weight (<1×10⁶ Da), strong permeability. Used for superficial dermal injection to improve skin quality (such as water light injection), but the duration is only a few weeks to a few months
Hyaluronic acid filler comparison chart

How long do hyaluronic acid fillers last?
Hyaluronic acid-based (HA) filler has become the most popular injectable augmentation preparation due to its biocompatibility, moderate length of efficacy (3–12 months), and reversibility of many complications using hyaluronidase.However, its use is not without complications.

What are the benefits of hyaluronic acid fillers?
1. Filling and shaping
Improve facial depressions: Fill depressions in temples, cheeks, tear grooves, apple muscles, etc. to restore fullness.
Contour modification: Used for shaping of chin, nose, lips, etc. (such as lip augmentation, rhinoplasty, chin padding), replacing traditional surgery.
Hand filling: Improve aging problems such as sagging skin on the back of the hand, exposed blood vessels and tendons.
2. Wrinkle removal and anti-aging
Static wrinkles: Fill fixed wrinkles caused by collagen loss, such as nasolabial folds, puppet lines, forehead lines, etc.
Dynamic wrinkle assistance: Combined with botulinum toxin (for dynamic lines), a more comprehensive rejuvenation effect is achieved.
3. Moisturizing and lifting
Lock in moisture and moisturize: Hyaluronic acid can absorb a large amount of water (up to 500 times its volume), improve skin dryness, and increase gloss.
Stimulate collagen: Hyaluronic acid with a low degree of cross-linking can promote collagen proliferation and improve skin elasticity.
4. Other applications
Joint lubrication: used in medicine for knee joint injection to relieve arthritis (but medical cosmetic fillers are special cross-linking processes and cannot be mixed).
Scar repair: softens depressed scars (such as acne scars).
Advantages
High safety: the human body contains hyaluronic acid, and the risk of allergies is low (preoperative skin test is required).
Reversibility: if the effect is not satisfactory, hyaluronidase can be used to dissolve it.
Immediate effect: the effect is visible immediately after injection, and the recovery period is short.




Contraindications:
- Injection is prohibited in areas with active infection or inflammation.
- Active autoimmune disease (such as lupus erythematosus)
- History of allergy to lidocaine or HA
- Pregnancy and lactation (limited evidence, avoidance recommended)
Future development direction: Expand national sales, let China go to the world, let the whole country see Made in China, and let medical beauty cover all parts of the country.
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